384 PCR CoolBlock – Precision Cooling for High-Density PCR Workflows

The 384 PCR CoolBlock is a high-precision, thermally conductive cooling block engineered for secure and uniform temperature control of standard 384-well PCR plates. Designed to meet the demands of modern high-throughput molecular biology applications, this CoolBlock ensures rapid and even cooling—critical for maintaining sample integrity during preparation, handling, and transport.

Crafted from anodized aerospace-grade aluminum, the 384 PCR CoolBlock provides superior thermal conductivity and chemical resistance. It eliminates the need for ice or ice baths by offering a stable, reusable, and contamination-free alternative that integrates seamlessly into benchtop workflows or cold-chain protocols.

🔍 Key Features & Benefits

✅ Compatible with All Standard 384-Well Plates

• Accommodates standard skirted and semi-skirted 384-well PCR plates

• Provides a snug, stable fit for secure handling and reduced risk of plate warping or shifting

❄️ Uniform, Ice-Free Cooling

• Delivers even temperature distribution across all 384 wells

• Prevents temperature gradients and edge effects, ensuring more accurate and reproducible qPCR and PCR results

⚙️ Rapid Temperature Transfer

• Made from solid anodized aluminum with high thermal conductivity

• Allows for fast temperature equilibration when used with ice packs, cold rooms, or dry ice-free systems (e.g., CoolBox™, CoolRack™)

🔬 Enhanced Sample Integrity

• Maintains nucleic acid and enzyme stability

• Ideal for workflows involving real-time PCR, next-generation sequencing (NGS) library prep, genotyping, and clinical diagnostics

🧪 Lab-Grade Durability

• Resistant to corrosion, chemical exposure, and frequent cleaning

• Designed for long-term, repeated use without degradation or loss of thermal performance

💼 Typical Applications

• PCR/qPCR reaction setup and stabilization

• Enzymatic reactions requiring cold temperature holding

• Holding of samples prior to thermal cycling

• On-bench or in-field temperature-sensitive sample handling

• NGS library preparation and diagnostic assay setup

🔗 System Compatibility

• Fully compatible with:

  • CoolBox™, CoolRack™, and other dry ice-free lab cooling platforms

  • Bench-top cooling workflows

  • Cold transport or temporary cold storage solutions

♻️ Sustainable and Reusable

Unlike single-use ice baths or gel packs, the 384 PCR CoolBlock provides a clean, reusable, and eco-conscious alternative that supports green laboratory initiatives while reducing costs and contamination risks.