One of the most widely used body fluids for the molecular diagnosis of human diseases is blood. Human whole blood consists of plasma (~55% of total blood volume), buffy coat (including white blood cells plus platelets, ~1% of total blood volume), and red blood cells (~45% of total blood volume). The extraction of nucleic acid from whole blood is an essential step for DNA/RNA-based diagnosis. [2]

In nucleic acid detection, the traditional method of extracting and detecting nucleic acid has lower efficiency, complex protocols, expensive instrumentation and requires highly skilled staff. Therefore, the automation of experiments has attracted great attention of researchers. Using magnetic particles to develop automatic nucleic acid detection technology, greatly simplifies the experimental process and improves the experimental efficiency and accuracy. [3]

Nucleic acids hold great significance in laboratory and on site testing of diseases. Already developed ways of testing can be improved further with the help of automatisation and novel extraction techniques, heightening the level of possibilities of nucleic acids for laboratory testing, disease prevention and diagnosis.